Inductively Coupled Plasma – Mass Spectrometry (ICP-MS)

Inductively Coupled Plasma – Mass Spectrometry (ICP-MS) is an ultra-sensitive analytical technique used for the detection and quantification of trace and ultra-trace levels of metals and several non-metals in various sample matrices. At SIMA LABS, ICP-MS enables precise multi-elemental analysis with exceptional sensitivity and low detection limits—making it indispensable for pharmaceutical, environmental, nutraceutical, food, cosmetic, and industrial testing. The method supports compliance with international standards such as ICH Q3D, USP <232>/<233>, and various EPA and ISO guidelines.

Key Offerings:

Pharmaceuticals

Elemental impurity analysis in drug products and raw materials to comply with ICH and USP requirements.

Environmental Monitoring

Trace metal analysis in drinking water, industrial effluents, and soil to meet regulatory and ecological standards.

Industrial & Manufacturing

Quality control of metals and alloys, contamination screening in raw materials, and process monitoring.

Food and Nutraceuticals

Detection of toxic and nutritional elements in ingredients, finished products, and dietary supplements.

Cosmetics & Personal Care

Testing for heavy metals and banned substances to ensure consumer safety.

Academic and Research Institutions

Advanced elemental analysis for R&D, method development, and material characterization across scientific disciplines.

Applications

Inductively Coupled Plasma–Mass Spectrometry (ICP-MS) is a highly sensitive and precise analytical technique used for the detection and quantification of trace and ultra-trace elements. Renowned for its ability to analyze a wide range of elements simultaneously, ICP-MS is essential across pharmaceutical, environmental, food, nutraceutical, cosmetic, and industrial sectors—ensuring regulatory compliance, safety, and quality in diverse sample types.

ICP-MS can detect elements at parts-per-trillion (ppt) levels, offering one of the lowest detection limits among elemental analysis techniques.

Yes, with proper sample preparation and method validation, ICP-MS delivers highly accurate results even in complex sample matrices.

We follow ICH Q3D, USP <232>/<233>, EPA, ISO, and FSSAI guidelines based on the sample and industry requirements.

Absolutely. It can simultaneously quantify a wide range of elements—from essential minerals like iron and zinc to toxic heavy metals like lead and mercury.

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