[HPTLC] High Performance Thin Layer Chromatography.
At SIMA LABS, we utilize advanced X-Ray Diffraction Analysis (XRD) to examine the structure of crystalline materials, including atomic arrangement, crystallite size, and defects. As a non-destructive and powerful technique, XRD offers detailed insights into crystallographic structure, chemical composition, and physical properties, making it essential for research in chemicals, pharmaceuticals, food, nutraceuticals, herbal products, organics, and oils.
Comprehensive HPLC Analysis
Key Offerings:
- Assay of pharmaceutical formulations and drug products
- Impurity profiling for active ingredients
- Quantification of vitamins and aflatoxins
- Pesticide residue analysis in food and water samples
Pharmaceutical Industry
HPLC plays a vital role in pharmaceuticals by enabling accurate purity testing, impurity profiling, and stability analysis. It measures active ingredients for correct dosage, detects trace impurities for quality control, and tracks degradation products to assess shelf-life.
Nutraceutical Industry
HPLC is vital in nutraceutical testing, ensuring the purity and accurate quantification of bioactive ingredients for reliable labeling and product quality. It verifies active ingredient levels to support health claims and screens for heavy metals to meet safety standards.
Biomolecular Analysis
HPLC enables detailed analysis of proteins, peptides, and biomolecules across research and clinical applications. It assesses protein purity, identifies peptides, and measures enzyme activity to support biomedical and biopharmaceutical studies.
Food Industry
HPLC is essential for food quality testing by accurately detecting vitamins, aflatoxins, and pesticide residues. It ensures correct nutritional labeling, identifies harmful aflatoxins in grains and nuts, and verifies pesticide levels to meet safety regulations.
Environmental Testing
HPLC is widely used for environmental monitoring by detecting pollutants in water and soil. It measures organic contaminants in water, analyzes pesticide runoff, and ensures treated wastewater meets regulatory discharge standards.
Cosmetic Quality Control
HPLC ensures ingredient purity in cosmetics, particularly in natural formulations, to meet safety and regulatory standards. It analyzes essential oils and fragrance compounds, and verifies preservative levels to maintain product stability and protect consumers.
Applications of HPLC
High-Performance Liquid Chromatography (HPLC) is a versatile analytical technique used across pharmaceuticals, food, nutraceuticals, environmental, and cosmetic industries. It enables precise quantification and identification of active ingredients, impurities, contaminants, and biomolecules—ensuring product quality, regulatory compliance, and safety in complex sample matrices.
HPTLC is an advanced version of Thin Layer Chromatography that offers higher resolution, sensitivity, and faster analysis. It uses automated sample application, precise solvent delivery, and digital detection systems for enhanced accuracy and reproducibility.
We analyze a wide range of samples including pharmaceuticals, herbal formulations, nutraceuticals, cosmetics, food products, and natural extracts.
HPTLC allows for rapid multi-sample analysis, high throughput, minimal solvent usage, cost-effectiveness, and simultaneous qualitative and quantitative assessment.
How is HPTLC used in pharmaceutical testing?
HPTLC is used for identity testing, impurity profiling, assay of active ingredients, stability studies, and content uniformity in pharmaceutical products.
Yes, HPTLC is ideal for fingerprinting herbal extracts, verifying bioactive components, and detecting adulteration or contamination in nutraceuticals and herbal medicines.
Absolutely. HPTLC at SIMA Labs is performed in accordance with pharmacopoeial standards (e.g., USP, EP, IP) and validated methods to meet global regulatory requirements.
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